You can log into your Office 365 webmail account to manage some of these settings, such as editing a blocked senders list.
This is because those settings are managed from the Exchange server. The most obvious reason for the option to be greyed out or unavailable: you arent looking at a message in the Junk Email folder Outlook is using for junk mail. NOTE: you will notice from the screen shot above that “Junk Email Preferences” is greyed out. Outlook For Mac Junk Email Preferences Greyed Out - cooldloa. You can also right-click on the relevant message and choose the Junk Mail option from the dropdown list, or choose the Rules option to set up a rule that determines what happens the next time you receive mail from that sender. The Best Office Productivity Tools Kutools for Excel Solves Most of Your Problems, and Increases Your Productivity by 80 Office Tab Brings Tabbed interface. Under Reply once to each sender with, enter your automatic reply. To do so, select the relevant message, then under the Home tab, look for the Junk icon and choose one of the options from the dropdown menu. In the Autoreply Settings box select the account on the left you want to setup the out of office reply, check the Send automatic replies for account 'X' box (where 'X' is the account you'd like to send out of office replies from). However, you can still use the Mark as Junk, Not Junk, or Block Sender options from within Outlook 2016 for Mac. Instead, all filtering is done at the server level, before the mail has even reached your Inbox. Unlike Outlook 2011 for Mac, there is no client-side junk mail filtering in the 2016 version.